Effects of Geographical Area and Harvest Times on Chemical Composition and Antibacterial Activity of Juniperus communis L. Pseudo-Fruits Extracts: A Statistical Approach

The beneficial effects of Juniperus communis L. extracts have been known for a long time. Therefore scientific knowledge the chemical profile leading to this bioactivity is required. aim paper highlight influence geographical origin and harvest time on compositional elements hydroalcoholic J. pseudo-fruits, but also their antibacterial properties. samples were collected from three mountainous area Romania, during consecutive months. total polyphenols determined by Folin-Ciocâlteu method, ranging between 12.67 14.77 mg GAE/g DW. High-performance liquid chromatography (HPLC) analysis was applied identify fifteen phenolic compounds group acids flavonoids. effect assessed Gram-positive Gram-negative bacterial strains. A good antimicrobial activity achieved pseudo-fruits harvested October November Iezerele Cindrelului Botanical Nature Reserve. obtained results denote diverse composition active principles in common juniper moderate dependent area.